Iron

Toxic Metal: Metal, Poison, Heavy Metal, Beryllium, Iron, Trace Element, Metalloid, Dimethylmercury, Tetra-Ethyl Lead, Carcinogen, BioaccumulationIron


Modern scientists-oncologists start to acknowledge: iron is not ordinary carcinogen. Iron is Global Omnipresent Carcinogen. However, the pathogenic role of iron in cancer development and/or progression is not fully understood. Why? Scientists ignored and ignore results/data of American cancer researches-1905: tumor cells contain so-called “masked” difficult-calculable iron. Modern scientists cannot understand information-1905 about “masked” iron into cells. [“masked” iron = nano-crystalline iron = ferromagnetic iron]. That is why any modern cancer research is as if boloney or rot. Majority of modern scientists considers iron is an essential element for dividing cells, because it is incorporated in numerous enzymes that play a role in DNA replication and cellular metabolism.
Question for children: can atoms of iron create crystal of iron? Opinion of Greatest Professor E.D.Weinberg and other “super-clever” iron researchers: atoms of iron cannot create nano-crystals of iron into any cells. I sent and send to cancer researchers information concerning official scientific data 1905-2010 on so-called "masked" iron into cells; opinion of the Bible on iron. Humanity will beat cancer very soon. You can see information on unconditional Victory of the Iron Conception-2006 (...“In the beginning of the XXI century humanity gets rid of cancer. One day, cancer will be chained to the “iron chains”...) http://www.tutuz.com/?p=445 Of course, Victory of the Iron Conception-2006 is terrible financial tragedy for some cancer researchers and organizations.
In a current of 4 years (2006-2010) global cancer research organizations play very interesting game: ‘Misunderstanding and silence’. I offer the global cancer research organizations very interesting police & judicial game-2010-2014: ‘Property confiscation, arrest of favorite bank accounts and liquidation of the favorite pseudo-research organization’. The life is a game.
The electronic version of article (analysis of iron-cancer connection; the hypothesis of penetration of ferromagnetic particles …, carcinogenic role of cellular iron) is the complete one and can be found online at: http://www.biomedcentral.com/1471-2407/4/1 (Iron: a target for the management of Kaposi's sarcoma?)
Kaposi's sarcoma (KS) is a mesenchymal tumour associated with human herpesvirus-8 infection. However, the incidence of human herpesvirus-8 infection is far higher than the prevalence of KS, suggesting that viral infection per se is not sufficient for the development of malignancy and that one or more additional cofactors are required.
Epidemiological data suggest that iron may be one of the cofactors involved in the pathogenesis of KS. Iron is a well-known carcinogen !!! and may favour KS growth through several pathways. Based on the apoptotic and antiproliferative effect of iron chelation on KS cells, it is suggested that iron withdrawal strategies !!! could be developed for the management of KS. Studies using potent iron chelators in suitable KS animal models are critical to evaluate whether iron deprivation may be a useful anti-KS strategy.
It is suggested that iron may be one of non-viral co-factors involved of KS pathogenesis and that iron withdrawal strategies might interfere with tumour growth in patients with KS.
HHV-8 is a necessary, albeit not sufficient, cause of KS and that one or more additional cofactors are required. These co-factors may represent a target for the prevention and/or treatment of KS. High incidence of KS in iron oxide-rich volcanic clays: Endemic KS in Africa predated the HIV epidemic and showed evidence of geographic restriction suggesting a genetic or an environmental cofactor. The highest prevalence of endemic KS in Africa lies in a broad strip running from the Uganda, Sudan, and Democratic Republic of Congo border southwards through Rwanda and Burundi. In the Northeastern provinces of the Democratic Republic of Congo, and in Rwanda and Burundi, KS accounts for up to 17% of adult male malignancies. Prevalence diminishes rapidly away from this endemic region. Amazingly, these areas of high prevalence of endemic KS are characterised by a common geologic substratum, composed of iron oxide-rich volcanic clays. This observation led Dr. Ziegler to suggest that chron
ic exposure to volcanic clays plays a role in the pathogenesis of African-endemic KS. His intriguing hypothesis was that ultrafine particles of clay penetrate the skin of the feet during barefoot walking, leading to dermal lymphatic damage and to impaired local immunity. Further data have strengthened the hypothesis of soil exposure and percutaneous penetration of ferromagnetic particles !!! as a risk factor for KS. More particularly, barefoot walking, time spent in contact with water and exposure to wet soils appear as important risk factors for KS in Uganda. In water, a clay emulsion disaggregates into particles less than 2 μm, a size that can readily enter sweat glands of the feet. While cultivating (especially in the rainy season when clay soils are pliant and workable), soil particles might thus enter the sweat glands and pores of the feet, perhaps aided by micro-abrasions caused by the high quartzite content of these soils.
In this perspective, we have reported the case of a metallurgist with classic KS involving his palm. Iron filings were detected in the underlying cutaneous tissues by magnetic resonance imaging, supporting the hypothesis that percutaneous penetration of iron may favour the development of KS. (Minerals of the geological substratum with massive release of fine particles of iron oxides and iron hydroxides.).
Exposure to volcanic clays may also help to explain the distribution of classic KS in the Mediterranean, prevalent in volcanic regions such as the Pelopenese, Sardinia and Sicily. Supporting this hypothesis, Montella et al. noted that the risk of classic KS was twofold higher among people born near Mount Vesuvius than among people born in neighbouring areas. Interestingly, a magmatic substrate similar to that of the East African Rift system (extrusive igneous rocks composed of mafic (and hence iron oxide-rich minerals)) is also present in Iceland and in the Faroe Islands which are other geographic areas known to exhibit surprisingly high incidence rates of classic KS. One of the characteristics of these mafic minerals is that they are highly weatherable, allowing a significant release of iron compounds in the environment, such as in water or in vegetables. The unusually high prevalence of the classic and endemic forms of KS in regions of intercontinental rifts and volcanism m
ay thus point to prolonged exposure to indigenous iron oxide-rich volcanic soils as a common aetiological risk factor.
Carcinogenic role of iron!!! Several observations have been made linking cellular iron content to the development of cancers. In prospective studies in animals, administration of excessive amounts of injected or oral iron increases markedly the risk of adenocarcinomas, colorectal tumours, hepatomas, mammary tumours, mesotheliomas, renal tubular cell carcinomas, and sarcomas. In humans, injections of iron complexes have been observed to result in sarcomas at the sites of deposition. Similarly, inhalation of industrial sources of iron may be responsible for respiratory tract neoplasias. Patients with hemochromatosis, a genetic disease characterised by increased iron absorption, show a markedly enhanced susceptibility to primary liver cancer and various other malignancies. Patients with moderate elevation of body iron levels may also have an increased risk of neoplasms of various kinds.
The pathogenic role of iron in cancer development and/or progression is not fully understood. (!!!) Several carcinogenic pathways have schematically been described: (a) iron is an essential element for dividing cells, because it is incorporated in numerous enzymes that play a role in DNA replication and cellular metabolism. More particularly, iron can directly promote the growth of some cancer cells, probably through its role in the activation of ribonucleotide reductase, a key-enzyme in DNA synthesis, responsible for the reduction of ribonucleotides to deoxyribonucleotides; (b) iron may promote the formation of mutagenic hydroxyl radicals; (c) iron excess diminishes host defences through inhibition of the activity of CD4 lymphocytes and through the suppression of the tumoricidal action of macrophages; (d) iron can enhance host cell production of viral nucleic acids which may be involved in the development of some human cancers. Other data support more specifically a direct r
ole of iron in the pathogenesis of KS: 1) the addition of iron salts to KS-derived cells can stimulate their growth; 2) iron can induce the expression of anti-apoptotic signals in human dermal microvascular endothelial cells, which may alter the homeostasis of microvessels and promote neo-angiogenesis. Interestingly, one of the histological hallmark of KS is the presence of ferritin granules and the presence of haemosiderin-laden macrophages. Even at the early 'patch-stage' of KS development, red blood cell extravasation and the presence of siderophages are encountered, providing a possible continuous source of iron for endothelial and KS cells.
Iron status in individuals prone to develop KS. Amazingly, a high iron load is expected to be found in the different epidemiological forms of KS. Iron load is elevated in renal transplant recipients who had received blood transfusions for years before the availability of erythropoietin and before transplantation. Iron load could also be higher in patients with episodes of haemolytic anaemia which are common features in Central Africa or in Mediterranean areas, mostly secondary to glucose-6-phosphatase deficiency, thalassemia or sickle cell anaemia. In HIV infection, the alteration of iron metabolism has been recognised in a variety of ways. The majority of patients in advanced stages of AIDS are hypoferrimic and moderately hyperferritinemic, and they have increased deposition of iron-ferritin and/or haemosiderin in cells of the bone marrow, brain white matter, skeletal muscle, and sometimes in the liver. The 'iron hypothesis' may also provide a non-hormonal explanation for th
e lower prevalence of KS among women, as they are known to have lower iron reserves than men. In this connection, it may also help to understand the reported disappearance of KS lesions during or just after pregnancy. It is interesting to note that there are high incidence rates of KS among Bantu in the South African Transvaal and that these individuals are known to frequently suffer from iron overload resulting from the interaction between their genotype and an environmental factor – namely, increased amounts of bioavailable iron in the diet. The source of this dietary iron is a traditional fermented beer that is home-brewed from local crops in steel drums.
Iron withdrawal strategies: a role for the management of KS? Based on a possible role of iron in tumour development, several studies have shown that iron withdrawal strategies possess considerable activity in vitro in inhibiting tumour growth. More particularly, we found that the chemically unrelated iron chelators desferrioxamine (DFO) and deferiprone could inhibit the growth and induce the apoptosis of human KS-derived cells at clinically achievable concentrations, suggesting that iron chelation may represent an experimental therapeutic approach for the treatment of KS. Iron chelators have also been shown to inhibit vascular cell adhesion molecule-1 (VCAM-1) expression in human dermal microvascular cells. As VCAM-1 may favour angiogenesis and account for inflammation-augmented tumour development and as it is used by cancer cells to enhance metastatic implantation and spread, VCAM-1 inhibition represents another mechanism through which iron chelation might prevent KS growth.
We previously initiated studies investigating the effect of DFO on the growth of immortalized KS-Y1 cells in immunodeficient mice, which resulted in paradoxical enhancement of the growth of the xenografts. These results could be related to the upregulation of angiogenic growth factors by DFO as well as to its short half-life in mouse plasma and to its subsequent inability to induce significant iron depletion in non-iron-overloaded mice. Another disadvantage of DFO is its poor ability to permeate cell membranes and bind intracellular Fe pools. Obviously, investigation of iron chelators showing higher iron chelation and use of animal models closely mimicking human KS are required.
… These molecules affect the expression of several molecules involved in cell cycle through their ability to chelate intracellular iron. As PIH analogues may have potential as agents to treat cancer, they represent potential drugs for KS therapy. Another promising chelator with greater efficacy than DFO is ICL670A, which is an orally active representative of a new class of tridentate iron chelator developed for the treatment iron overload and which has been shown to be relatively well-tolerated in phase III studies.
Summary. At present, several types of iron withdrawal strategies have been shown to possess considerable activity in vitro in inhibiting tumour growth. Based on the probable role of iron in KS pathogenesis, it is suggested that manipulations of iron load might interfere with tumour growth in patients with KS. However, further studies using potent iron chelators in suitable KS animal models are critical to evaluate whether iron deprivation may be a useful anti-KS strategy.
UCLA's Jonsson Comprehensive Cancer Center, Dr. Elizabeta Nemeth ((enemeth[at]mednet.ucla.edu)) is interested in regulation of iron metabolism and the pathogenesis of iron disorders. There are multiple interactions between Iron Metabolism and Cancer. On one hand, iron overload promotes carcinogenesis. At the other end of the spectrum, cancer-related inflammation leads to iron-restriction, hypoferremia and anemia of cancer. Her goal is to understand the interactions between cancer and iron metabolism and use the knowledge to develop appropriate therapeutic interventions.
Dr. Elizabeta Nemeth (Der zukünftige Nobelpreisträger) ist an der Regelung des Eisenmetabolismus und der Pathogenese der Eisenstörungen interessiert. Es gibt mehrfache Interaktionen zwischen Eisenmetabolismus und Krebs. Einerseits fördert Eisenüberlastung Karzinogenese. Am anderen Ende vom Spektrum, führt Krebs-in Verbindung stehende Entzündung zu Eisenbeschränkung, hypoferremia und Anämie von Krebs. Ihr Ziel ist, die Interaktionen zwischen Krebs und Eisenmetabolismus zu verstehen und das Wissen zu verwenden, um passende therapeutische Interventionen zu entwickeln.
The Journal of Medical Research, Cornell University Medical College, New York, November, 1905 gives detailed data concerning so-called “masked” iron into tumor cells. American cancer researchers-1905 used dilute acids for liberation of “masked” iron from its organic condition (environment). http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2100013/?page=1
The Research Institute, Royal Cancer Hospital, London, April, 1939: “…The determination of Fe (estimations of the Fe contents) in biological material is notoriously difficult…Evidence of the lability of the additional Fe (abnormal deposit of Fe) has been obtained…”. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1264440/?page=1
Internal Diseases, Volume 6, Chapter 3, Anemias, Prof. Andrei Arkadievich Bagdasarov, Prof. Mark Solomonovich Dulzin (Laureates of the Stalin Prizes), Moscow, 1962, page 120: “More 15% of iron into organism IS iron-without-calculation (accounting, registration).”. [Свыше 15% железа (в организме) не поддаётся учёту.]. [Iron Stalin gave Stalin Prizes only outstanding scientists.].
Page 242: “It is self-evident, growth of malignant tumor is accompanied by higher deposition of iron into tumor tissue.”. [Понятно, что рост злокачественной опухоли сам по себе сопровождается повышенным депонированием железа в опухолевой ткани.].
Honest American (1905), English (1939) and Soviet (1962) cancer researchers [Многотомное Руководство по Внутренним Болезням, том 6, Болезни Системы Крови и Кроветворных Органов, Москва 1962, глава 3, Анемии, Патогенез анемий, Анемия при раковом новообразовании.] AFFIRM: tumor cells (tissues) contain so-called “masked” additional difficult-calculable iron. Soviet outstanding scientists, researchers of iron metabolism, are astonished: where is 15% of iron?
I affirm: any cells (human, animal or vegetative), particularly tumor cells, contain “self-masked” difficult-calculable nano-crystalline ferromagnetic iron = basis (primary root cause) of any oncopathology.
Crystallization of iron or crystallization of catalase or crystallization of hemoglobin or crystallization of myoglobin into cells IS ordinary process. See, for example, H.Theorell, Kristallinische Myoglobin. Biochem. Ztschr., 1934, 268, 55-63.
Some modern researchers of NCI, CRUK, DKFZ and other Cancer Research Establishments make global useless researches; make powerful engulfment of budgetary money. These researchers like money, but fear to pronounce words CRYSTALLIZATION and FERROMAGNETISM. They affirm: presence of excessive iron (free iron, hem iron and unhem iron) into organism is the next in turn, the usual, well-known onco-factor (and diabetes-factor and hemochromatosis-factor). Honest ‘old’ scientists-oncologists discover and describe numerous chemical carcinogens. Georges Mathe, Dossier cancer, 1977, wrote: ‘‘Asbestos (CaO*3MgO*4SiO), Cr, Ni, Cd, Pb, Sn, Fe, As … are carcinogens.”. Dear cancer researchers! These chemical carcinogens can take the form of nano-crystals into cells. Lovely Au can take the form of big crystals into banks.
Ms Alice Victor, the Cancer Association of South Africa, 14 July 2010, wrote: “Thank you for contacting CANSA’s Information Service. Dr Carl Albrecht, Head of our Research answers your questions as follows: Like most pseudo-science, there is some truth and the rest is junk. Iron can cause liver cancer. One of CANSA’s researchers Prof Michael Kew showed this. But then to extrapolate that all cancer comes from iron is nonsense.”.
Opinion of Honest African onco-Professors = opinion of American NCI-Directors-Laureates = opinion of CRUK, DKFZ, French, Russian onco-Professorate: Fe is ordinary chemical carcinogen; Fe can cause liver cancer; Fe can cause hemochromatosis. [Can Fe cause schizophrenia (or cancer of mind) of modern cancer researcher?].
Sensational opinion of Vadim Shapoval: Fe is ‘the God’ of oncogenesis / carcinogenesis / tumorigenesis.
Of course, Fe can ‘work’ as ordinary chemical carcinogen. People (who extracted iron ore 200 years ago) often received cancer of lung. Today smokers often receive cancer of lung.
Thanks to modern onco-Professorate, ‘the God’ of oncogenesis receives very modest title: ordinary chemical carcinogen. Excellent scientific camouflage. Some Russian cancer researchers invent polyetiological theory of cancer. What for? For camouflage of ‘the God’ of oncogenesis?
True, root, MOLECULAR-BIOLOGICAL CAUSE of any oncopathology? Modern researchers of NCI, CRUK, DKFZ and other Cancer Research Establishments have no settled opinions. In my opinion-2006: presence of so-called “masked” (“self-masked”) additional difficult-calculable nano-crystalline ferromagnetic iron into cells IS true, root, molecular-biological cause of any oncopathology. The God nonpluses “super-clever” and opinionated cancer researchers by means of primitivism. The Holy Writ shows unequivocally: iron is loathsome substance.
Oncopathology can start even into iron-deficiency organism or into iron-normal organism, because any human organism, any human organ, any human cell contains numerous atoms of iron. [Cell is as if iron-containing reservoir. Congestion of dead cells is important and ‘often’ onco-factor.]. Atoms of iron can create nano-crystals of iron. Atom of iron + atom of iron + atom of iron + … + atom of iron = nano-crystal of iron = crafty ferromagnetic occupant. Of course, presence of excessive iron into organism intensifies, accelerates or starts neoplastic processes. Diverse biological, chemical and physical onco-factors [combinations of these onco-factors] (crystalline onco-viruses, crystalline chemical carcinogens, radiation, very caloric nourishment, nervous shocks, free radicals, congestion of dead cells, etc.) lead to beginning of mass iron crystallization into cells; to oncopathology. Ultra-accurate iron-deficiency methods of treatment of oncopathologies are panacea.
Cancer researchers! Super-cleverest Professors, Directors, Greatest Nobel Laureates, MD and PhD! Can you understand by means of super-cleverest brains school words: crystallization and ferromagnetism? You want to invent ‘clever’ non-primitive antitumor medicaments. You want to make mistakes for budgetary money. Stop! Crystallization and ferromagnetism are school terminology. Some cancer researchers must go to school to read ‘primitive’ schoolbooks.
Scientists attempted to develop/realize penicillin’s ideas in 1870, in 1928. Only to 1940, Americans made crystalline penicillin. Scientists liked and like to make numerous misunderstandings and mistakes. Soviet Stalin made for some Soviet scientists travelling to Siberia to gold-extractions. Crystalline gold is super-wonderful substance, beloved substance for some modern cancer researchers. Chinese Mao made Cultural Revolution for Chinese corrupt scientists. Can President Obama make American Cultural Revolution-2010 for some modern American cancer researchers (and thermonuclear researchers)? [55 years mad thermonuclearists attempt to hold plasma by means of powerful double-pole magnetic fields. What for? I don’t know.].
So, biochemists attempted and attempt to explain neoplastic and degenerative anomalies into cells by means of biochemical reasonings. In vain. J. P. Greenstein, Biochemist and Investigator of Cancer, pessimistically wrote: "I don't know why, but researches in sphere of cancer are cemeteries for many scientific reputations.".
Chemistry shows: CELL is aggregation (assembly) of atoms and molecules.
Biology shows: CELL is aggregation of organelles.
Physics shows: CELL is aggregation of dia-, para-, ferri- and ferromagnetic pico.....nano.....micro- objects.
I can explain numerous onco- and degenerative anomalies into any tumor cells by means of school Physics + Biology + Chemistry. ‘Biochemical cancer researchers’ cannot explain these anomalies by means of Biology + Chemistry.
Pure water is the main diamagnetic substance. Crystalline onco-viruses and crystalline chemical carcinogens are weak-magnetic substances into cells. Crystalline (nano-crystalline) iron is the main ferromagnetic substance into any cells. Crystalline (nano-crystalline) hem iron and unhem iron are the auxiliary dia--->---para--->---ferrimagnetic substances into any cells.
Accurate iron-deficiency (iron-sequestration) methods can rescue many Onco-, Neuro- and AIDS-patients (enzymes's systems of virus-AIDS die under 'accurate iron-deficiency conditions'). Molecular-biologically, any oncopathology and ALS base on intracellular nano-crystalline iron.
Can you understand, appreciate, use or/and publish information concerning consolidated physical+biological+chemical look at the CELL?
I read the ferromagnetic theory of cancer/oncogenesis into the Holy Writ. Can the Holy Writ contain information concerning future thermonuclear and rocket technologies (for neo-USSR)? Black gold will die soon (secret information). Iron horses and iron birds must eat liquid oxygen + liquid hydrogen. Agreed?
You can read about unconditional Victory of the ferromagnetic theory of cancer (Iron Conception) into illegible forecasts of Evangelia Dimitrova (Vanga, Bulgaria). In 1994, she prophesied: “In the beginning of the XXI century humanity gets rid of cancer. One day, cancer will be chained to the “iron chains”. She explained these words in such a way that the “cure for cancer should contain a lot of iron.”. http://www.tutuz.com/?p=445
I think: contain = connect. Problems with translation of Macedonian dialect and breast cancer neutralized E.Dimitrova in 1996. She was prophetess, but not scientist-oncologist. She saw only future sensational headlines of all newspapers and journals: “Humanity beats cancer…IRON…contain…decreasing…”.
Sincerely, Vadim I. Shapoval, author of the ferromagnetic theory-2006 of oncogenesis, August 1, 2010
http://ftcancer.blogspot.com/ or http://ferromcancer.wordpress.com/
[[[Intracellular iron metabolism is very intricate metabolism.
Vadim Shapoval' intracellular iron metabolism: 1] atomic (ionic, free) iron; 2] various forms of hem iron; 3] various forms of unhem iron; 4] nano-crystals of iron; 5] nano-crystals of hem iron; 6] nano-crystals of unhem iron.
Invalid intracellular iron metabolism: 1]; 2]; 3].
You can choose between 1];2];3];4];5];6] and 1];2];3]. Between truth and half-truth. Ignorance of data concerning of crystallization of iron (and other substances) into cells IS lunatism.
4] = ‘the main difficult-calculable iron’ = ‘primary ferromagnetic matter’ = ‘ferromagnetic infection’ = basis of onco-, some neuro- and some other diseases.
5] and 6] = ‘accessory difficult-calculable iron’, dia--->---para--->---ferrimagnetic matter.
If you open any old molecular-biological Atlases, then you can see very numerous and very diverse diamagnetic and paramagnetic nano-crystals (quadrates, rhombs, lozenges, various many-sides figures, tubular structures) into any cells (human, animal or vegetative). All onco-viruses are crystalline para--->---ferrimagnetic matter. [Viruses and toxic chemical substances can kill cells. Dead cells are iron-containing reservoirs.].
Millions various chemical crystalline substances live/are formed into cells. Crystallization is ordinary process that is present into any cell. Crystalline substances can occupy mitochondrions, cytoplasm, membrane, etc. Ferromagnetism is property of crystalline substances. Atom of iron is non-ferromagnetic matter.
Linear, non-periodical//non-regular, moving negative-charged crystal (DNA) creates around oneself magnetic field. Such crystal (moving negative-charged) is possessed of magnetic field. Nano-crystals of iron are possessed of magnetic fields also. In such a manner (superposition of local magnetic fields) nano-crystals of iron guarantee various numerous mutations into tumor or degenerative cells. Cancer researchers like to describe, describe, describe and describe these mutations. What for? Researches for the sake of researches.
Magnetic fields of nano-crystals of iron can anarchically distort DNA of the cell; can deform//uglify mitoses (genetic material stops to be distributed properly, chromosomes do not disperse but tear, etc.). Nano-crystals of iron travel from maternal tumor cell to daughterly tumor cells with portions of cytoplasm, membrane and other organelles (ungenetic inheritance of neoplastic properties). Nano-crystals of iron are inherited even if the genetic material of the cell is not damaged. Any tumor cell is normal cell that is taken ill ‘ferromagnetic infection’ (nano-crystalline iron sand).
Harold Varmus, M.D., co-recipient of a Nobel Prize for studies of the genetic basis of cancer, was nominated by President Obama as Director of the NCI on May 17, 2010. Can President Obama send American schoolbook ‘Physics’ (chapters Crystallization and Ferromagnetism) to Greatest and Cleverest Director of the NCI?
Any atoms, any molecules, any proteins, any enzymes, even Au !!!, can create nano.....micro-crystals into cells. Atom of iron + atom of iron + atom of iron + ...+ atom of iron = crystal of iron. Molecule of catalase + molecule of catalase + molecule of catalase + … + molecule of catalase = crystal of catalase. Is it clear? No? Eugene Weinberg, Professor (87 years), Greatest American ironic expert, does not understand school information concerning crystallization of atoms and molecules in Nature, into cells. Greatest Professor Weinberg can investigate and eat crystalline salt (NaCl) and crystalline sugar (for brain).
Physical (magnetic) sorts of intracellular nano-crystals: 1) diamagnetic nano-crystals; 2) paramagnetic nano-crystals; 3) ferrimagnetic nano-crystals; 4) ferromagnetic nano-crystals.
Diamagnetic ('non-magnetic') nano-crystals and paramagnetic (weak-magnetic) nano-crystals into cells are as if ‘non-dangerous’ nano-crystals. Ferri- and ferromagnetic (strong-magnetic) nano-crystals into cells are fatal nano-crystals. Why? Toxicity? No. Ferromagnetism. Physicists explain ferromagnetism (quantum phenomenon) by means of magnetic properties of electrons (see old Soviet schoolbooks).
1) Ferri/omagnetic intracellular nano-crystals attract (by means of invisible magnetic fields) various numerous paramagnetic useful!!! atoms, molecules, free radicals, proteins, enzymes, other para-, ferri-, ferro- nano-crystals. You can explain mechanism of some neurodegenerative pathologies (ALS, etc.) by means of deficiency of useful free!!! molecules, proteins, enzymes into neurons. [[According to Otto H. Warburg, Nobel Laureate, cancer should be interpreted as a mitochondrial dysfunction. Warburg wrote: “But, even for cancer, there is only one prime cause. Summarized in a few words, the prime cause of cancer is the replacement of the respiration of oxygen in normal body cells by a fermentation of sugar.". Cancer researchers must eat crystalline sugar! The respiratory-sugar theory of Krebs IS very interesting theory. Respiratory problems can attack tumor cells. Why? I think: nano-crystals of iron attract and as if neutralize atomic iron and respiratory pigments; create
respiratory problems into tumor cells.]]. Electron microscopes cannot see/identify legibly such "chaotic anarchic mush" into tumor and degenerative cells. Onco-viruses can disappear into tumor and degenerative cells! Magic? Fantasticality? No. Insidious "chaotic anarchic mush" hides / masks / disguises / camouflages onco-viruses. Crystalline iron is “self-masked” iron into cells. Chemical analysis of intracellular crystalline iron is very difficult task. Why? Thousands various para- and ferri- and ferro-magnetic intracellular substances are reliable environment of any intracellular nano-crystal of iron. Honest American cancer researchers-1905 used dilute acids for liberation of “masked” (nano-crystalline) iron from its organic condition (environment). Some modern American cancer researchers think only about super-wonderful crystalline bank gold.
2) Ferri/omagnetic intracellular nano-crystals change some properties of cells, cell-cell interactions. You can explain mechanism of any oncopathology (human, animal or vegetative) by means of action of local magnetic fields that 'are born' into intracellular ferri- and ferromagnetic nano-crystals.
Modern cancer researchers know and describe biochemical processes into cells ultra-well. My sincere congratulations. If cancer researchers can open Holy Writ, old schoolbooks 'Physics' or old molecular biological Atlases, then they can legibly explain etiology of numerous onco-, some neuro- and some other iron-related disorders.
Soviet medical literature affirms: “Hemochromatosis and sideroblastic anemia ( = iron overload diseases) very often lead to any oncopathology (sooner or later manifesting leucosis, sarcoma or liver cancer).”. Of course, any oncopathology can start, even, into iron-deficiency organism, because any human cell contains atomic (ionic, free) iron. According to iron logic, even 0,5 gram of intracellular nano-crystalline iron can kill any human being. Everyone has potential ‘iron onco-ticket’ to Heaven (or Hell). Tumor likes to deposit iron. Tumor can create deficiency of iron (atomic, hem and unhem) into organism. Naive kind doctors give oncopatients iron medicaments, recommend iron diet.
Brilliant American Internet affirms: “Infection plays an important role in the etiology of spontaneous disruption of tumor with their metastases.”. “Expansion of the purulent infection may result in spontaneous regression of tumor.”. Why? I think purulent infection creates ‘successful deficiency of iron’ into organism of oncopatient.
Oncopatients die, because some modern ‘super-clever’ cancer researchers (Professors, Directors, Laureates, MD, PhD, etc.) ununderstand and fear to pronounce school words CRYSTALLIZATION and FERROMAGNETISM. Wonderful crystalline bank gold prevents adequate cancer researches.
Conclusion. American, New York, researches-1905; English, London, researches-1939; Soviet, Moscow, researches-1962 and Vadim Shapoval, researches-2006 AFFIRM: any normal and tumor tissue contains so-called “masked” additional difficult-calculable iron. Such iron (“self-masked” intracellular nano-crystalline ferromagnetic iron) is ‘the God’ of oncogenesis / carcinogenesis / tumorigenesis.
Always is present, ‘ready at hand’, Consolidator of all ferro(i)magnetic (and carcinogen’s) substances, inner enemy = intracellular nano-crystalline iron IS matter-monopolist for any tumor process. ‘The explanation of cancer problem should be looked for not only in carcinogens, but in the CELL itself’, - Hans Lettre wrote. Hans! At-a-Boy! Diverse biological, chemical and physical onco-factors [combinations of these onco-factors] lead to beginning of mass creation of nano-crystals of iron into cells. Millions nano-crystals of iron can occupy space of tumor cell; electron microscopes cannot show distinctly such ferromagnetic occupants.
Intracellular nano-crystals of iron attract and encircle (by means of invisible magnetic fields) various numerous paramagnetic atoms, molecules, free radicals, proteins, enzymes, metabolites, fragments of organelles, crystalline viruses, other para-, ferri-, ferro- nano-crystals. That is why electron microscopes cannot see/identify legibly such "chaotic anarchic mush" into tumor and degenerative cells. ‘Tumor cells contain suspicious B- and C-particles’, - Rudolf Suss wrote. Rudolf! At-a-Boy!
Nano-crystals of iron are “self-masked” intracellular iron. Some Cancer Research Establishments = Powerful Accumulators of Dollars (pad) cannot understand Iron-Cancer/Krebs American-English-Russian-German information 1905-2010 without police and judicatory persecutions; without disgrace.
Old Medical encyclopedia, tumors: “It is stated that tumor cells are characterized by signals of Electron Paramagnetic Resonance (EPR) different from such signals of homologous normal cells. Influences that leads to regression of the tumor or retardation of it growth is paralleled by normalization of EPR signals of tumor cells.”.
Huth E.F. noticed: suppurative processes repress leucoses. [Huth E.F. Zum Antagonismus zwischen bakteriellen Infektionen und malignen Erkrankungen. Med. Klin., 1958, 53, 2173-2277]. Why is it so? Suppuration needs of atomic (free) iron. Deficiency of atomic iron represses oncopathology. ‘Medical artificial accurate deficiency of atomic iron’ can repress any oncopathology or/and slow (sluggish) virus//bacterial association (AIDS, etc.).
Greatest onco-Professorate-2010 must read schoolbooks about crystallization and ferromagnetism.]]].

By: Vadim I. Shapoval